After waiting an extra month to decide on the H3N2 strain, World Health Organization (WHO) vaccine advisors today finalized their recommendations on strains to include in the Northern Hemisphere 2019-20 flu vaccines.Their H3N2 recommendation—an A/Kansas/14/2017-like virus—reflects a change from the current Northern Hemisphere vaccine and is not a component of the Southern Hemisphere 2019 flu vaccines, either.New subclade rising sharply in US, elsewhereWhen making the announcement on the 2009 H1N1 and influenza B components at the end of their meeting in February, the experts noted increased numbers of genetically and antigenically diverse strains, with the number of clade 3C.3a viruses rising in several geographic regions.In its update today, the WHO said the proportion of viruses falling into that clade has increased substantially since November in several countries in western Europe, Israel, and especially the United States.H3N2 viruses pose an increasing challenge for experts picking the vaccine strains because of frequent changes in the virus and problems making flu vaccine seed strains.In its background materials today, the WHO said the delayed decision marks the second time the advisory committee has delayed a recommendation. In 2003, the group also took another month to observe developments with antigenically distinct H3N2 viruses.Delay could affect vaccine supply…Delays in announcing recommendations and major changes in recommended strains can increase the risk of delays in vaccine manufacturing process.The WHO said all stakeholders are working together to minimize the threat of delayed vaccine supply and availability as much as possible. For example, it said one of the steps is intensive work by collaborating labs to ensure that manufacturers have access to a high-yielding vaccine virus for production.To account for possible delays, the WHO advised countries to prepare for a possible 2- to 4-week delay in vaccine supply and to consider extending time for vaccination programs.…but probably worth gamble, expert saysScott Hensley, PhD, associate professor of microbiology at the University of Pennsylvania’s Perelman School of Medicine, said on Twitter today that he liked the WHO group’s recommendation. He said both 3C.3a. and 3C.2a viruses are currently circulating.”It is not certain if 3C.3a will continue circulating next year, but if they do, this vaccine will likely have decent VE [vaccine effectiveness],” he wrote.For the past 2 years, egg-adapted 3C.2a vaccines have had low VE, even against 3C.2a viruses, so it’s probably worth the risk of updating to 3C.3a, Hensley said. Another advantage is egg-adaption problems that have plagued 3C.2a viruses don’t seem to affect 3C.3a ones, so VE will probably be high if that subclade circulates next season.”This situation really highlights the importance of basic research of influenza virus evolution,” he wrote, adding, “Our ‘educated guesses’ of what might circulate next year are much better today compared to 10 years ago, but we still have a lot to learn.”See also:Mar 21 WHO flu vaccine strain recommendation addendumMar 21 WHO FAQFeb 21 CIDRAP News story “WHO changes H1N1 flu vaccine strain, punts on H3N2″Scott Hensley Twitter posts
The city’s planning committee granted planning permission for the Rogers Stirk Harbour + Partners masterplan on the 26-acre site following two years of public consultation. The site is around Cambridge’s Station Road area and the masterplan includes over 570,000 sq ft of offices; 331 residential units; student accommodation for 1,250 Anglia Ruskin University students; a 120-bed hotel; a new station square, transport interchange and station concourse; 56,000 sq ft of retail; and community facilities. Sven Topel, group development and investment director of Ashwell, said: ‘With the Masterplan for this strategic site now approved the city of Cambridge is a significant step closer to getting the world-class gateway it deserves.’ David Tannahill, Network Rail commercial development manager, said: ‘Over the past two years we have worked closely with Ashwell to create a scheme that will deliver significant improvements to Cambridge station, benefiting the local community and passengers.‘These improvements are the direct result of consultation with our rail industry partners. We can now move forward with this scheme with Ashwell.’ Ashwell will now draw up detailed designs for a series of detailed planning applications.
Jalur LRT Jabodebek Kuningan -Dukuh Atas (detik.com) Pekerjaan pembangunan jalur Light Rapid Transit (LRT) yang menghubungkan Jakarta, Bogor, Depok Bekasi (Jabodebek) masih terus berjalan. Namun lintasan yang menghubungkan kawasan Kuningan menuju kawasan Dukuh Atas saat ini pengerjaannya masih tertahan di Jalan H.R Rasuna Said Kuningan.Baca juga: Sambut Asian Games 2018, LRT Jakarta Siap Beroperasi 10 Agustus MendatangDari pantauan yang dilakukan KabarPenumpang.com beberapa hari lalu, sudah mulai terlihat pengerjaan. Apalagi bisa dikatakan lintasan Kuningan menuju Dukuh Atas merupakan yang paling baru dalam umur pengerjaannya. Adapun pengerjaan yang ada adalah sebagian bentangan panjang jalur LRT di Jalan Rasuna Said sudah terpasang dan sebagian lainnya masih dalam tahap pembangunan pondasi dan pengamanan pengerjaan. Sebab pengerjaan lintasan Kuningan-Dukuh Atas sendiri berada tepat di tengah jalur jalan Rasuna Said.Meski progres terlihat, namun masih tertahan dikarenakan belum selesainya penetapan lokasi untuk jalur yang dilalui dari Setiabudi sampai ke Dukuh Atas.“Sinkronisasi trase di Setiabudi sampai ke Dukuh Atas yang masih belum selesai sehingga belum bisa kita lakukan konstruksinya,” ujar Direktur Operasi II Adhi Karya Pundjung Setya Brata yang diutip KabarPenumpang.com dari detik.com, Selasa (17/7/2018).Brata mengatakan, penetapan lokasi masih belum rampung karena tertahan penentuan posisi lokasi stasiun yang ada di DUkuh Atas. Ini seperti yang diketahui bahwa Dukuh Atas sendiri akan menjadi pusat dari segala transportasi massal yang ada di Jakarta nantinya seperti MRT, KRL, TransJakarta, LRT baik Jakarta maupun Jabodebek sendiri.“Apakah di sisi utara atau selatan. Ada dua alternatif yang masih perlu disepakati oleh pihak Kemenhub sama Pemprov DKI,” ujarnya.Baca juga: Viral Suzuki Jimny Nongkrong di Atas Rel LRT Sumatera Selatan. Ada Apa?Bila penetapan lokasi yang akan dikeluarkan oleh Peprov DKI Jakarta sudah diputuskan, maka pihak Adhi Karya akan langsung melanjutkan pekerjaan menuju Dukuh Atas. Progres pekerjaan jalur LRT Jabodebek lintasan Kuningan-Dukuh Atas sendiri saat ini baru mencapai 25,6 persen. Sementara untuk lintasan secara total progresnya 41 persen.Selain kemacetan, salah satu dampak dari pembangunan jalur LRT juga terlihat dengan dibangunnya halte TransJakarta baru yang diakibatkan oleh jalan yang menyempit.Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Like this:Like Loading… RelatedDilengkapi 17 Stasiun, LRT Jabodebek Siap Mengular di 202113/07/2019In “Darat”LRT Jabodebek Siap Uji Coba, Bagaimana Tarif, Headway dan Kapasitas Keretanya?17/10/2019In “Darat”Pembebasan Lahan Tuntas, LRT Jabodebek dan Kereta Cepat Jakarta-Bandung Mengular 202113/12/2019In “Darat”
Shanghai officials reveal novel coronavirus transmission modes Where did they go? Millions left Wuhan before quarantine La Salle’s head coach had his head down, acknowledged no one, and immediately embraced the huge wooden crucifix, the same way he did when he won his NCAA basketball title with Colegio De San Juan de Letran.It’s the culmination of arguably the most infamous coaching raid in collegiate sports history, Ayo had to lead the Green Archers to a title a year after he led the Knights to an inspiring championship run in the NCAA. “Each championship is unique but I can say this is more difficult because of the pressure,” said Ayo after beating Ateneo 79-72 in Game 2 of the UAAP basketball finals.READ:Big adjustments yield championship for Teng, ArchersAyo led the most talented team in UAAP Season 79 with Ben Mbala, who waited three years to play, joining Jeron Teng, Abu Tratter, Andrei Caracut, Kib Montalbo, Prince Rivero, and rookie Aljun Melecio.It was championship or bust for Ayo and his team, but that pressure was something the architect of the “Mayhem” defense wanted.But the stakes got higher in the finals and teir 13-1 record was put to test against a pesky and youthful Ateneo side.ADVERTISEMENT “We embraced the pressure all season long, then we got to the Finals against Ateneo the more the pressure got heavier because of the hype due to the rivalry,” said Ayo. “Bottomline, it’s basketball, whatever they have, and whatever we have it will show on the court.”Sports Related Videospowered by AdSparcRead Next We are young Senators to proceed with review of VFA PH among economies most vulnerable to virus MOST READ La Salle head coach Aldin Ayo celebrates the UAAP Season 79 championship. Photo by Tristan Tamayo/INQUIRER.netCelebration rang inside the historic Smart Araneta Coliseum as confetti rained down on the jubilant Green Archers from De La Salle University.Players had their separate friends and family embracing them, each with their own championship shirt.ADVERTISEMENT Mainland China virus cases exceed 40,000; deaths rise to 908 As fate of VFA hangs, PH and US forces take to the skies for exercise EDITORS’ PICK View comments Next challenge for Blue Eagles is to ‘live up to our potential’ Just before the eruption of euphoria exploded, however, Aldin Ayo made a quick exit; he headed down the corridor that separated the playing court to the backstage.READ: La Salle sweeps Ateneo to capture UAAP Season 79 crown FEATURED STORIESSPORTSGinebra teammates show love for SlaughterSPORTSWe are youngSPORTSFreddie Roach: Manny Pacquiao is my Muhammad Ali Chinese-manned vessel unsettles Bohol town Smart’s Siklab Saya: A multi-city approach to esports Don’t miss out on the latest news and information. Taiwan minister boards cruise ship turned away by Japan PLAY LIST 01:31Taiwan minister boards cruise ship turned away by Japan01:33WHO: ‘Global stocks of masks and respirators are now insufficient’01:01WHO: now 31,211 virus cases in China 102:02Vitamin C prevents but doesn’t cure diseases like coronavirus—medic03:07’HINDI PANG-SPORTS LANG!’03:03SILIP SA INTEL FUND Smart hosts first 5G-powered esports exhibition match in PH
The idea of refrigerating mooncakes strikes local bakers as odd, if not ridiculous. “Never have people put mooncakes in the refrigerator,” said Linda Lee, a supervisor at Kee Wah Bakery in Monterey Park. “You can ask any Chinese person. It’s not like dumplings. You can’t microwave them.” Preliminary tests have shown that mooncakes do not have the moisture level that would render them a “potentially hazardous food,” said Hector Dela Cruz, acting chief environmental health specialist with the Los Angeles County Health Department. Dela Cruz said studies are ongoing, and the department will await results of the state’s study for a definitive ruling. Similar challenges to health codes arose in the 1990s when East Coast-style eateries began selling pizza by the slice. Rather than requiring the slices be refrigerated, officials determined there was no health risk if the pizza was consumed in four hours. Pasadena, however, has its own health department, and regulated mooncakes differently. “Mooncakes are a perishable food item which need to be refrigerated most of the time,” said Mel Lim, an environmental health division manager, who added the cakes would need to be refrigerated after two hours. Meantime, preparations push ahead in other cities for the annual celebration. Helen Wong stuck gold stickers on wrapped mooncakes at Best Bakery in Alhambra, pausing to point out the main ingredients in a mooncake: pineapple, sugar, flour and oil. Other mooncake varieties include those that contain lotus seed, red bean and date paste, sometimes with nuts embedded inside. Wong compared the salted egg yolk to more familiar Western food. “It’s just like you don’t refrigerate beef jerky,” she said. [email protected] (626) 578-6300, Ext. 4586160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set! AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREThe joys and headaches of holiday travel: John PhillipsBut local bakers are puzzled by what the fuss is all about. “I’ve been in the business 12 years and nothing like this has ever come up,” said Duong, who owns Royal Bakery in Rosemead. Duong estimates he sells about 100 boxes of mooncakes daily as the festival approaches. If stored in a cool area, he said the mooncakes will keep for a month without going bad. The cakes, which often come in boxes of four, are passed around as gifts between relatives, friends and business associates during the festival season. They consist of a thin brown crust, imprinted with intricate patterns of Chinese characters and pictures, enveloping a sweet, dense paste. Despite public health officials’ recent concern over the shelf-life of cultural fare, customers at Dennis Duong’s bakery streamed in and out on a recent afternoon, picking up stacks of boxes of a Chinese delicacy called mooncakes. With the Mid-Autumn Festival coming up Friday, the dessert is in high demand. The hockey-puck shaped pastry is as essential as turkey on Thanksgiving in the Chinese celebration, which also goes by the name Mooncake Festival. The concern was great enough in Orange County to prompt Assemblyman Van Tran, R-Costa Mesa, to author a bill urging the California Department of Health Services to conduct a study to see if the shelf life of mooncakes and two types of Vietnamese rice cakes, bahn tet and bahn chung, can be extended. Gov. Arnold Schwarzenegger signed the legislation last week. A report is due by January 2008.